Herpes encephalitis treatment steroids

The outcome of the disease varies and depends on factors such as initial cause, age, severity of the case, and strength of the immune system. For example, people who are HIV positive, have cancer , or who have other illnesses have a weaker immune system and are less able to withstand another disease. These patients have a wide range of outcomes that range from good to poor. In general, those people with mild cases and otherwise relatively good health usually will recover without any problems. Poorer outcomes can be summarized as follows:

Other types of arboviral encephalitis include the following:

  • Japanese (widespread in Asia)
  • Murray Valley (endemic in Australia)
  • Powassan (transmitted by ticks; occurs in Canada and the northern United States)
  • Tick-borne (occurs throughout Europe; vaccine available)
  • Venezuelan equine (common in Central and South America)
Secondary Encephalitis —This type develops as a complication of a viral infection or reactivation of a latent virus. Viruses can become reactive when the immune system is suppressed by other conditions (., malnutrition, stress, disease). Infections that may cause secondary encephalitis include influenza, chickenpox (varicella-zoster), measles (rubeola), mumps, and German measles (rubella).

These viruses look identical under the microscope, and either type can infect the mouth or genitals. In the 1960's, the distinction was made that HSV-1 occurs above the waist, and HSV-2 below, but genital HSV-1 infections are increasing.

Herpes Simplex Type 1 (HSV-1) is the virus usually responsible for oral herpes or cold sores. If you receive unprotected oral sex from someone who has (HSV-1) cold sores, you can get genital herpes, or HSV-1 on your genitals.

Herpes Simplex Type 2 (HSV-2) or genital herpes is usually below the waist, but if you perform oral sex on someone who has HSV-2 genital sores, you can get HSV-2 on your face and mouth area.

HSV can also infect other parts of the body. Some other areas could be the eyes and the brain. Herpes Encephalitis is herpes in the brain. Very rare, and only affecting 2 per million, encephalitis is very dangerous and can cause a sore throat, headache, fever, vomitng, coma, and even death if left untreated.

Herpesviral Encephalitis can be treated with high-dose intravenous acyclovir . Without treatment, HSE results in rapid death in approximately 70% of cases; survivors suffer severe neurological damage. [1] When treated, HSE is still fatal in one-third of cases, and causes serious long-term neurological damage in over half of survivors. Twenty percent of treated patients recover with minor damage. Only a small population of survivors (%) regain completely normal brain function. [4] Indeed, many amnesic cases in the scientific literature have etiologies involving HSE. Earlier treatment (within 48 hours of symptom onset) improves the chances of a good recovery. Rarely, treated individuals can have relapse of infection weeks to months later. There is evidence that aberrant inflammation triggered by herpes simplex can result in granulomatous inflammation in the brain, which responds to steroids. [7] While the herpes virus can be spread, encephalitis itself is not infectious. Other viruses can cause similar symptoms of encephalitis, though usually milder ( Herpesvirus 6 , varicella zoster virus , Epstein-Barr , cytomegalovirus , coxsackievirus , etc.).

Herpes encephalitis treatment steroids

herpes encephalitis treatment steroids

Herpesviral Encephalitis can be treated with high-dose intravenous acyclovir . Without treatment, HSE results in rapid death in approximately 70% of cases; survivors suffer severe neurological damage. [1] When treated, HSE is still fatal in one-third of cases, and causes serious long-term neurological damage in over half of survivors. Twenty percent of treated patients recover with minor damage. Only a small population of survivors (%) regain completely normal brain function. [4] Indeed, many amnesic cases in the scientific literature have etiologies involving HSE. Earlier treatment (within 48 hours of symptom onset) improves the chances of a good recovery. Rarely, treated individuals can have relapse of infection weeks to months later. There is evidence that aberrant inflammation triggered by herpes simplex can result in granulomatous inflammation in the brain, which responds to steroids. [7] While the herpes virus can be spread, encephalitis itself is not infectious. Other viruses can cause similar symptoms of encephalitis, though usually milder ( Herpesvirus 6 , varicella zoster virus , Epstein-Barr , cytomegalovirus , coxsackievirus , etc.).

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