Corticosteroid ointment for eyes

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In an open-label HPA axis safety trial in subjects 3 months to 12 years of age with atopic dermatitis , DIPROLENE AF Cream % was applied twice daily for 2 to 3 weeks over a mean body surface area of 58% (range 35% to 95%). In 19 of 60 (32%) evaluable subjects, adrenal suppression was indicated by either a ≥ 5 mcg/dL pre-stimulation cortisol, or a cosyntropin post-stimulation cortisol ≥ 18 mcg/dL and/or an increase of < 7 mcg/dL from the baseline cortisol. Out of the 19 subjects with HPA axis suppression, 4 subjects were tested 2 weeks after discontinuation of DIPROLENE AF Cream, and 3 of the 4 (75%) had complete recovery of HPA axis function. The proportion of subjects with adrenal suppression in this trial was progressively greater, the younger the age group.

Corticosteroid ointment for eyes

corticosteroid ointment for eyes

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