Rather than attach too much significance to an individual test result, it makes good sense to monitor any trends in changes to your CD4 cell count over time. It’s best to have your CD4 count measured at the same clinic and at roughly the same time of day wherever possible. If you have another infection, such as the flu or an outbreak of herpes, talk to your clinic about whether it is best to delay your CD4 count until you are feeling better. If you get a result that is very different to that expected, your doctor may want to repeat the test to check whether the first result was a laboratory error.
The 4,6,8(14)-triene-3-one steroids, highly fluorescent in aqueous solutions, lose their fluorescence power when binding occurs to hydrophobic regions of other molecules, such as the hydrophobic cavity in the ring system of cyclodextrins. The fluorescence intensity decreases almost completely when β- and γ-cyclodextrins are present in the solution. Scatchard plots derived from fluorescence titrations show that one or two molecules of steroid bind to one cyclodextrin molecule with K D,F -values of about 10 −4 −10 −5 mol/liter. Temperature-jump experiments show a single relaxation process, with rate constants for the decay of the β-cyclodextrin-steroid complexes of about 10 4 −10 5 per s. For α- and γ-cyclodextrins such relaxation processes are not observed.